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ChiCTR2600119910
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2026-03-05
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Thyroid Cancer
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1.Discover new genetic mutations or variants associated with thyroid cancer that have not been previously documented 2.Analyze Common Mutations in Thyroid Cancer-Related Genes 3.Assess the Clinical Utility of NGS in Patient Management 4.Compare Genetic Variants Across Different Populations
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45
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2024-10-01
2025-09-30
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Patients were eligible for inclusion if they had a histopathologically confirmed diagnosis of PTC, underwent total thyroidectomy during the study period, and had available formalin-fixed, paraffin-embedded (FFPE) tumor tissue suitable for molecular analysis. Only cases with complete clinicopathological data, including demographic, biochemical, and tumor-related parameters, were enrolled.;
请登录查看Patients were excluded if they had any other histological type of thyroid cancer, presented with distant metastasis at the time of diagnosis, or had insufficient or poor-quality FFPE samples that failed DNA extraction or sequencing quality control. Individuals with recurrent thyroid cancer, previous thyroid surgery, radiotherapy, or systemic therapy were also excluded, as well as cases with incomplete medical records that could not be used for statistical evaluation.;
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