ChiCTR2400093928
尚未开始
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2024-12-13
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Impact of calligraphy practice on functional brain network
Effect of calligraphy practice on modulating default mode network in older adults at risk of dementia – a randomized controlled trial
The primary objective is to examine the effect of calligraphy practice on functional connectivities (FCs) within DMN. The secondary objective is to examine the effect of calligraphy practice on cognitive functions.
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其它
Participants will be randomly allocated to either the intervention or control group in a 1:1 ratio using a central computer-generated random number sequence.
Research staff who assist in intervention will not assess outcomes, and those who assess outcomes will be blinded to allocation and not involved in intervention delivery.
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100
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2025-01-01
2027-12-31
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Inclusion criteria are ethnic Chinese, aged 55 to 75 years, right-handed, living at home, and experiencing SCD as defined by i) scoring above the age- and education-specific cutoff for MCI (i.e., cognitive test performance within normal range) in the Hong Kong Chinese version of Montreal Cognitive Assessment (MoCA), and ii) answering yes to at least one question in the Abbreviated Memory Inventory for Chinese, a locally validated screening tool for SCD.；
请登录查看Exclusion criteria include living in care homes; known MCI or clinical dementia; having history of stroke, traumatic brain injury, Parkinson’s disease, epilepsy, brain tumor, or prior operation to the brain; taking drugs that affect cognition (benzodiazepines, cognitive enhancers, etc.); having history of depression, bipolar affective disorder, psychosis, or substance abuse; having significant impairment in communication, writing or mobility; previously learned or already practising Chinese calligraphy handwriting; already attending other cognitive interventions or participating regularly in other cognitive activities (≥1 hour per week; cognitive activities defined by the validated classification system of leisure activities in local older Chinese adults); and having magnetic resonance imaging (MRI) contraindications.；
请登录查看Chinese University of Hong Kong
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