ChiCTR2200065417
尚未开始
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2022-11-04
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Parkinson's disease
Home-based dyadic mindfulness yoga programme for patients with Parkinson's disease and their caregivers
A home-based dyadic mindfulness yoga programme for patients with moderate-advanced Parkinson’s disease and their family caregivers: a feasibility trial
1) To examine the feasibility and preliminary effects of a dyadic mindfulness yoga programme compared with usual care on the primary outcome (depression) and secondary outcomes (anxiety, social support, mindfulness, functional balance, HRQOL, caregiver burden and PD-related motor and non-motor symptoms) among PwPD and caregivers at one week post-intervention (T1) and three month post-intervention. 2) To explore the experiences of Chinese PwPD and their family caregivers in using the dyadic mindfulness techniques for illness coping using a qualitative research approach.
随机平行对照
其它
After baseline assessment, dyads will be randomly assigned into one of the two groups on a 1:1 basis using the method of permuted block, with random block sizes between 4 and 8, and will be informed of their assigned group by an independent person not involved in assessment.
All outcome assessors will be blinded to subject allocation.
Seed Fund for Basic Research
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30
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2022-11-01
2025-06-30
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We will recruit Chinese patients with idiopathic moderate-advanced PD (as indicated by the Hoehn and Yahr Scale stages III-IV: those with unilateral/bilateral symptoms, with/without postural instability who are able to walk or stand unassisted) and their family caregivers. For the patient, they need to be: 1. Aged between 50-80 years; 2. Experienced at least mild depressive symptoms–as indicated by a Patient Health Questionnaire-9 (PHQ-9) score >= 5 (15)–to ensure they are exposed to the core problem addressed by this study. As for the caregivers, they need to be self-identified as the primary co-residing caregivers of the patient counterparts for at least three months. Both of them need to be able to communicate in Cantonese. They will only be eligible if both the patient and caregiver in a dyad provide written consent to participate.；
请登录查看Exclusion criteria are: 1. Have been engaged in regular systematic mind-body practices such as Tai Chi, qigong, yoga or other forms of mindfulness training (> 2 times per week) in the past 3 months; 2. Have pre-existing acute psychotic disease; 3. Are currently participating in any other behavioural or pharmacological trial; 4. Have significant cognitive impairment as indicated by the Abbreviated Mental Test score <= 6; 5. Have other contraindication(s) that may limit their full participation (e.g., severe hearing or vision impairment, etc.).；
请登录查看The University of Hong Kong
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浙江道尔生物科技有限公司2026-04-16
新药创始人2026-04-16
丁香园 Insight 数据库2026-04-16
2021至2023年理赔服务2026-04-16
干细胞与外泌体2026-04-16
细胞与基因治疗领域2026-04-16
北京药研汇2026-04-16
正大天晴药业集团2026-04-16
复融生物2026-04-16
先通医药2026-04-16
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