ChiCTR-IPC-15006715
尚未开始
阿奇霉素+多西环素
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阿奇霉素+多西环素
2015-07-09
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Azithromycin, doxycyline, MGD, blepharitis, dry eyes
阿奇黴素 (Azithromycin) 和多西環素 (Doxycycline) 治療瞼板腺功能失調
阿奇黴素 (Azithromycin) 和多西環素 (Doxycycline) 治療瞼板腺功能失調
阿奇黴素 (Azithromycin) 和多西環素 (Doxycycline) 治療瞼板腺功能失調
横断面
Ⅰ期
Randomized
Double-blind
Hong Kong Medical Supplies Ltd (Thea Laboratories)
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50
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1990-01-01
1990-01-01
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1. Symptomatic meibomian gland dysfunction not responding to warm compresses, lid massage, and lubricants; 2. Older than 12 year old; 3. Able to give informed consent; 4. Able to comply with treatment and follow-up schedule.；
请登录查看1. On treatment for MGD or dry eye syndrome other than warm compresses, lid massage and lubricants in the past 3 months; 2. Schirmer's test without anaesthesia <5mm per 5 minutes in both eyes - Pretreatment LipiView score >=100 in both eyes; 3. Known allergy to tetracycline or macrolide; 4. Pregnant or breast feeding women; 5. Women planning pregnancy; 6. Hepatic impairment or on hepatotoxic drugs; 7. Severe renal impairment; 8. Ocular condition that causes similar symptoms and signs as MGD, including structural lid abnormalities, lagothalmos, conjunctivochalasis, contact lens wear, thyroid eye disease; 9. On systemic medications that may contribute to dry eye without being on a stable dose in the past 1 month.；
请登录查看Hong Kong Medical Supplies Ltd (Thea Laboratories)
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