【ChiCTR1900023045】A study for the relation among morphokinetic parameters, mitochondrial pattern and karyotype for better selection of embryos undergoing in vitro maturation
ChiCTR1900023045
尚未开始
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2019-05-08
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In vitro oocyte maturation
A study for the relation among morphokinetic parameters, mitochondrial pattern and karyotype for better selection of embryos undergoing in vitro maturation
A study for the relation among morphokinetic parameters, mitochondrial pattern and karyotype for better selection of embryos undergoing in vitro maturation
The aim of this study is to investigate the relations among morphokinetic parameters, mitochondria patterns and karyotype in order to decrease both the implantation failure rate and miscarriage rate of IVM embryos. The primary outcome of this study is to utilize the immature oocytes to increase the number of available embryo for improving the success rate of IVF by identifying the cytogenetic abnormal embryo through morphokinetic parameters. The second outcome is that we can increase our knowledge of meiotic error by studying the morphokinetic parameters and karyotype of immature oocytes.
单臂
探索性研究/预试验
N/A
N/A
No fuding
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100
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2019-06-01
2020-12-31
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All patients complied to the following selection criteria: 1) plan to undergo ICSI procedure; 2) have immature oocyte/s after denudation; once recruited patients have more than three fertilized oocytes and extruded polar bodies, we will collect their polar bodies through polar body biopsy.；
请登录查看1. male infertility due to one testicle had been removed, history of undescended testis, previous chemotherapy, testicular torsion; 2. Patients with azoospermia; 3. Patients with normal WHO (Version 5) in all parameters.；
请登录查看香港中文大學婦產科學系
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