ChiCTR2500111062
尚未开始
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2025-10-24
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acute myeloid leukemia
Maintenance Venetoclax Based Therapy Post Complete Remission In AML Fit Patients
Maintenance Venetoclax Based Therapy Post Complete Remission In AML Fit Patients
The aim of this study is to explore the efficacy of maintenance SC cytarabine + venetoclax therapy as regard disease free survival (DFS) in AML fit patients who achieved CR after highly aggressive chemotherapy as bridge for BMT or if BMT will be delayed or canceled due to any other reason.
随机平行对照
Ⅲ期
The randomization sequence will be generated by an independent statistician using a computer-based random number generator. Patients will be allocated in a 1:1 ratio to receive Venetoclax maintenance or placebo
Investigators and participants will remain blinded to the treatment allocation, ensuring that neither the enrollment process nor subsequent assessments are biased.
Sohag university
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40
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2025-11-01
2027-10-10
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1-Age : 18 - 60 years . 2-Patients who are not eligible for immediate bone marrow transplantation. 3-Newly diagnosed AML patients who attained CR after 1st line. 4-Refractory / recurrant AML patients .；
请登录查看1-Patients not on CR . 2-Age : younger than 18 or older than 60 3-Patients not eligible for bone marrow transplation；
请登录查看Sohag university
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