【ChiCTR2600132371】Building Resilience Against Rising Temperature - The Effect of High-Intensity Interval Exercise (HIIE) on Heat Tolerance, Thermoregulatory Adaptation, and Physical Fitness: A Comparative Randomized Controlled Trial
ChiCTR2600132371
尚未开始
/
/
/
2026-09-14
/
/
NA
Building Resilience Against Rising Temperature - The Effect of High-Intensity Interval Exercise (HIIE) on Heat Tolerance, Thermoregulatory Adaptation, and Physical Fitness: A Comparative Randomized Controlled Trial
Building Resilience Against Rising Temperature - The Effect of High-Intensity Interval Exercise (HIIE) on Heat Tolerance, Thermoregulatory Adaptation, and Physical Fitness: A Comparative Randomized Controlled Trial
1.To evaluate whether high-intensity interval training performed under thermoneutral environmental conditions improves physiological resilience to heat stress 2.To determine whether high-intensity interval training is the most effective exercise intervention to enhance heat resilience and thermoregulatory capacity compared with other traditional exercise types
随机平行对照
其它
Selected participants will then be randomly assigned to one of the four groups using a computer-generated randomization schedule. This process will ensure that the groups are comparable at baseline regarding age, gender, and fitness levels. Randomization will be conducted by an independent researcher who will not be involved in the intervention.
A blinded data analyst who is not involved in participant recruitment, intervention delivery, or outcome assessment will conduct the statistical analyses. Participants will be identified only by unique study codes, and no personally identifiable information will be provided to the analyst. Intervention allocation will be masked using coded group labels (e.g., Group A, B, C, and D), such that the analyst will not know which code corresponds to the HIIE, MICE, WALK, or control group during data cleaning and primary statistical analysis. The group allocation code will be revealed only after the primary analyses have been completed and finalized.
General Research Fund (GRF)
/
25
/
2026-09-23
2027-09-23
/
1. Ethnic Chinese adults aged 18–40 years. 2. Physically inactive, defined as engaging in less than 150 minutes of moderate-intensity physical activity per week. 3. Normal body weight (BMI <24 kg/m^2). 4. Free from chronic illnesses that would contraindicate exercise participation, such as cardiovascular diseases (including uncontrolled hypertension), metabolic disorders, or musculoskeletal injuries. 1. Ethnic Chinese adults aged 18–40 years. 2. Physically inactive, defined as engaging in less than 150 minutes of moderate-intensity physical activity per week. 3. Normal body weight (BMI <24 kg/m^2). 4. Free from chronic illnesses that would contraindicate exercise participation, such as cardiovascular diseases (including uncontrolled hypertension), metabolic disorders, or musculoskeletal injuries.；
请登录查看1. Individuals with a history of heat-related illness, recent surgery, or any medical condition that may impair their ability to safely participate in exercise. 2. Pregnant women and individuals currently taking medications that may affect thermoregulation or cardiovascular responses (e.g., beta-blockers, anticholinergic agents, stimulants, or other relevant medications). 3. Individuals with regular occupational or habitual heat exposure that may induce heat acclimation or acclimatization (e.g., outdoor workers or individuals who regularly use saunas).；
请登录查看The Chinese University of Hong Kong
/
The Chinese University of Hong Kong的其他临床试验
- Longitudinal and Moderating Effects of Repetitive Gain and Nonloss Framing on Self-Care, Digital Mental Health Platform Engagements, and Mental Health
- Feasibility, Acceptability and Effectiveness of a Tailored Multidimensional Intervention for Dementia Family Caregivers in Caregiving and Mental Health Crisis: A Pilot Randomised Controlled Trial
- One-step Rehydration Thawing Method in Frozen Embryo Transfer: A pragmatic randomized controlled clinical trial (ORT-FET-RCT)
- Feasibility and Acceptability of Cognitive Behavioural Stress Management Intervention (JoyMUM) for Pregnant Women: A Pilot Randomised Controlled Trial
- Building Resilience Against Rising Temperature - The Effect of High-Intensity Interval Exercise (HIIE) on Heat Tolerance, Thermoregulatory Adaptation, and Physical Fitness: A Comparative Randomized Controlled Trial
- Effects of Care partner Online Programme for Managing BPSD and Enhancing Wellbeing (COPE‑BPSD)
- Effects of Wearing a Sauna Suit During High-Intensity Interval Exercise
- Air purifier and respiratory outcomes in childhood asthma in compromised housing environments: a hybrid effectiveness-implementation trial
- To investigate structural variations (SVs) in autism spectrum disorder (ASD) and related endophenotypes
- Young Adult Community Health Advisor (YACHA)-led Project to Promote Anti-drug Awareness among South Asian Youths and their Family in Hong Kong
- Effects of High-Intensity Interval Training on Physical Fitness, Cognitive and Mental Health in Hong Kong Adolescents with Intellectual Disabilities: A Cluster-Randomized Controlled Trial
- The Effects of Low‐ and High‐Glycemic Index Sport Nutrition Bars on Metabolism and High‐Intensity Interval Training Responses
- An innovative approach to combine intermittent dieting (INTD) with high-intensity interval exercise (HIIE) for curbing central obesity: A comparative randomized controlled trial
- Effectiveness of acceptance-based diabetes self-management (ACT-DSM) for adults with type 2 diabetes for improving diabetes distress and glycaemic control: A randomised controlled trial
- Effects of GABA with Butyrate, GABA/Butyrate-producing Synbiotics on Pain Relief in Fibromyalgia: A Phase II, Multi-Center, Double-Blinded, Randomized-Controlled Trial
- The effects of art therapy-based intervention on anxiety children with haematological cancers: a randomised controlled trial
- Effectiveness of Digital CBT-I and BT-I combined ACT for Insomnia and Anxiety Symptoms in Youth: A Randomised Control Trial
- An evidence-based advance care planning programme to promote end-of-life care planning among patients with advanced diseases in the Emergency Department – a feasibility randomised controlled trial
- WhatsApp-assisted prehabilitation programme for adult patient undergoing elective colorectal cancer surgery
- Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Hepatobiliary and Pancreatic surgery
The Chinese University of Hong Kong的其他临床试验
- Longitudinal and Moderating Effects of Repetitive Gain and Nonloss Framing on Self-Care, Digital Mental Health Platform Engagements, and Mental Health
- Feasibility, Acceptability and Effectiveness of a Tailored Multidimensional Intervention for Dementia Family Caregivers in Caregiving and Mental Health Crisis: A Pilot Randomised Controlled Trial
- One-step Rehydration Thawing Method in Frozen Embryo Transfer: A pragmatic randomized controlled clinical trial (ORT-FET-RCT)
- Feasibility and Acceptability of Cognitive Behavioural Stress Management Intervention (JoyMUM) for Pregnant Women: A Pilot Randomised Controlled Trial
- Building Resilience Against Rising Temperature - The Effect of High-Intensity Interval Exercise (HIIE) on Heat Tolerance, Thermoregulatory Adaptation, and Physical Fitness: A Comparative Randomized Controlled Trial
- The effect of Sodium-Glucose Cotransporter-2 Inhibitors and Dipeptidyl Peptidase-4 Inhibitors on Diabetic Retinal Disease
- 运动与脑刺激疗愈：促进居住于分间楼宇单位的注意力缺陷多动障碍儿童症状控制的三臂随机对照试验
- Effects of Care partner Online Programme for Managing BPSD and Enhancing Wellbeing (COPE‑BPSD)
- Air purifier and respiratory outcomes in childhood asthma in compromised housing environments: a hybrid effectiveness-implementation trial
- To investigate structural variations (SVs) in autism spectrum disorder (ASD) and related endophenotypes
- Young Adult Community Health Advisor (YACHA)-led Project to Promote Anti-drug Awareness among South Asian Youths and their Family in Hong Kong
- Effects of High-Intensity Interval Training on Physical Fitness, Cognitive and Mental Health in Hong Kong Adolescents with Intellectual Disabilities: A Cluster-Randomized Controlled Trial
- A self-determination theory-based interprofessional intervention to improve diabetes management in the primary health care setting of Hong Kong
- The Effects of Low‐ and High‐Glycemic Index Sport Nutrition Bars on Metabolism and High‐Intensity Interval Training Responses
- An innovative approach to combine intermittent dieting (INTD) with high-intensity interval exercise (HIIE) for curbing central obesity: A comparative randomized controlled trial
- Effectiveness of acceptance-based diabetes self-management (ACT-DSM) for adults with type 2 diabetes for improving diabetes distress and glycaemic control: A randomised controlled trial
- Effects of GABA with Butyrate, GABA/Butyrate-producing Synbiotics on Pain Relief in Fibromyalgia: A Phase II, Multi-Center, Double-Blinded, Randomized-Controlled Trial
- 一项关于声刺激增强慢波睡眠以改善失眠障碍睡眠质量的探索性研究
- The effects of art therapy-based intervention on anxiety children with haematological cancers: a randomised controlled trial
- Effectiveness of Digital CBT-I and BT-I combined ACT for Insomnia and Anxiety Symptoms in Youth: A Randomised Control Trial
最新临床资讯
-
一项5年临床安全随访研究启示：#脐带间充质干细胞（#hUC-MSCs）
SCLnow圣释2026-11-11
-
SYNCHRONIZE-CVOT试验达到主要终点，索弗度肽（survodutide）成为全球首个证实心血管安全性的胰高血糖素/GLP-1双受体激动剂
勃林格殷格翰中国2026-11-11
-
医药观澜2026-11-11
-
宜明昂科2026-11-11
-
医学科学院精准医学研究所2026-11-11
-
多肽圈2026-11-11
-
多肽圈2026-11-11
-
求是网2026-11-11
-
干细胞之父2026-11-11
-
和田维药2026-11-11
全球药物研发中心
全球研发数据与行业前沿情报
研发动态
相关报告
政策法规
-
2026-11-12
-
2026-11-12
-
2026-11-12
-
摩熵咨询 20 3
-
摩熵咨询 33 60
-
摩熵咨询 20 3
-
颁布机构：国家卫生健康委办公厅、 2026-11-10
-
颁布机构：国家卫健委（原国家卫计委） 2026-11-10
-
颁布机构：国家药品审评中心（CDE） 2026-10-16
同适应症药物临床试验
医药市场洞察中心
医药市场销售数据分析 · 智能洞察 · 竞争格局监测
-
医药市场销售数据分析 · 医院、实体药店、网上药店
-
市场竞争格局分析(靶点、药品类型、ATC大类)
市场动态
市场报告
政策法规
-
2026-11-11
-
2026-11-11
-
2026-11-11
-
摩熵咨询 35 92
-
摩熵咨询 28 74
-
摩熵咨询 34 49
-
颁布机构：国家市场监督管理总局 2026-11-07
-
颁布机构：国家市场监督管理总局 2026-11-07
-
颁布机构：国家市场监督管理总局 2026-11-04