【ChiCTR2600132371】Building Resilience Against Rising Temperature - The Effect of High-Intensity Interval Exercise (HIIE) on Heat Tolerance, Thermoregulatory Adaptation, and Physical Fitness: A Comparative Randomized Controlled Trial

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基本信息

登记号

ChiCTR2600132371

试验状态

尚未开始

药物名称

药物类型

规范名称

首次公示信息日的期

2026-09-14

临床申请受理号

靶点

适应症

试验通俗题目

Building Resilience Against Rising Temperature - The Effect of High-Intensity Interval Exercise (HIIE) on Heat Tolerance, Thermoregulatory Adaptation, and Physical Fitness: A Comparative Randomized Controlled Trial

试验专业题目

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临床试验信息

试验目的

1.To evaluate whether high-intensity interval training performed under thermoneutral environmental conditions improves physiological resilience to heat stress 2.To determine whether high-intensity interval training is the most effective exercise intervention to enhance heat resilience and thermoregulatory capacity compared with other traditional exercise types

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试验类型

随机平行对照

试验分期

其它

随机化

Selected participants will then be randomly assigned to one of the four groups using a computer-generated randomization schedule. This process will ensure that the groups are comparable at baseline regarding age, gender, and fitness levels. Randomization will be conducted by an independent researcher who will not be involved in the intervention.

盲法

A blinded data analyst who is not involved in participant recruitment, intervention delivery, or outcome assessment will conduct the statistical analyses. Participants will be identified only by unique study codes, and no personally identifiable information will be provided to the analyst. Intervention allocation will be masked using coded group labels (e.g., Group A, B, C, and D), such that the analyst will not know which code corresponds to the HIIE, MICE, WALK, or control group during data cleaning and primary statistical analysis. The group allocation code will be revealed only after the primary analyses have been completed and finalized.

试验项目经费来源

General Research Fund (GRF)

试验范围

目标入组人数

实际入组人数

第一例入组时间

2026-09-23

试验终止时间

2027-09-23

是否属于一致性

入选标准

1. Ethnic Chinese adults aged 18–40 years. 2. Physically inactive, defined as engaging in less than 150 minutes of moderate-intensity physical activity per week. 3. Normal body weight (BMI <24 kg/m^2). 4. Free from chronic illnesses that would contraindicate exercise participation, such as cardiovascular diseases (including uncontrolled hypertension), metabolic disorders, or musculoskeletal injuries. 1. Ethnic Chinese adults aged 18–40 years. 2. Physically inactive, defined as engaging in less than 150 minutes of moderate-intensity physical activity per week. 3. Normal body weight (BMI <24 kg/m^2). 4. Free from chronic illnesses that would contraindicate exercise participation, such as cardiovascular diseases (including uncontrolled hypertension), metabolic disorders, or musculoskeletal injuries.；

排除标准

1. Individuals with a history of heat-related illness, recent surgery, or any medical condition that may impair their ability to safely participate in exercise. 2. Pregnant women and individuals currently taking medications that may affect thermoregulation or cardiovascular responses (e.g., beta-blockers, anticholinergic agents, stimulants, or other relevant medications). 3. Individuals with regular occupational or habitual heat exposure that may induce heat acclimation or acclimatization (e.g., outdoor workers or individuals who regularly use saunas).；

研究者信息

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试验机构

The Chinese University of Hong Kong

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